• Mark Tommerdahl, Oleg Favarov, Christina D Wagner, Timothy J Walilko, Laila Zai, and Timothy B Bentley.
• Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Cortical Metrics, LLC, Carrboro, NC 27599, USA.
• Mil Med. 2022 Oct 29; 187 (11-12): e1363e1369e1363-e1369.

IntroductionThe Office of Naval Research sponsored the Blast Load Assessment Sense and Test (BLAST) program to develop a rapid, in-field solution that could be used by team leaders, commanders, and medical personnel to provide a standardized approach to operationally relevant monitoring and analysis of service members exposed to single or repeated low-level blast. A critical piece of the BLAST team's solution was the development of the Brain Gauge technology which includes a cognitive assessment device that measures neurofunctional changes by testing sensory perceptions and a suite of mathematical algorithms that analyze the results of the test. The most recent versions of the technology are easily portable; the device is in the size and shape of a computer mouse. Tests can be administered in a matter of minutes and do not require oversight by a clinician, making Brain Gauge an excellent choice for field use. This paper describes the theoretical underpinnings and performance of a fieldable Brain Gauge technology for use with military populations.Materials And MethodsThe methods used by the Brain Gauge have been documented in over 80 peer-reviewed publications. These papers are reviewed, and the utility of the Brain Gauge is described in terms of those publications.ResultsThe Brain Gauge has been demonstrated to be an effective tool for assessing blast-induced neurotrauma and tracking its recovery. Additionally, the method parallels neurophysiological findings of animal models which provide insight into the sensitivity of specific metrics to mechanisms of information processing.ConclusionsThe overall objective of the work was to provide an efficient tool, or tools, that can be effectively used for (1) determining stand-down criteria when critical levels of blast exposure have been reached and (2) tracking the brain health history until return-to-duty status is achieved. Neurofunctional outcome measures will provide the scientific link between blast sensors and the impact of blast on biological health. This calibration process is strengthened with outcome measures that have a biological basis that are paralleled in animal models. The integrative approach that utilizes the Brain Gauge technology will provide a significant advance for assessing the impact of blast exposure and support rapid, science-based decision-making that will ensure mission success and promote the protection of brain health in service members.© The Association of Military Surgeons of the United States 2021. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

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