• Brandi Molina, Gerald Glickman, Prashanthi Vandrangi, and Mehrzad Khakpour.
• Department of Endodontics, Baylor College of Dentistry, The Texas A&M University System Health Sciences Center, Dallas, Texas.
• J Endod. 2015 Oct 1; 41 (10): 1701-5.

IntroductionStudies using conventional endodontic protocols show insufficient cleaning of root canal systems, often resulting in persistent infection and treatment failure. The GentleWave System (GWS; Sonendo, Inc, Laguna Hills, CA) has been shown to result in a higher tissue dissolution rate in a study using bovine muscle. The purpose of this study was to compare the debridement efficacy of the GWS with a traditional method for cleaning root canals.MethodsForty-five freshly extracted molars were randomly separated into 3 treatment groups (n = 15/group): group 1, no treatment; group 2, conventional rotary instrumentation and needle irrigation; and group 3, minimal instrumentation and the GWS treatment. Roots were prepared per standard histologic tissue processing after hematoxylin-eosin staining; sections were microscopically examined, and the percentage of soft tissue and debris remaining within the canals was morphometrically calculated. Images of the apical and middle regions of the roots were blindly analyzed.ResultsSignificant differences (Welch's t test) were found between groups 2 and 3 in both apical (P = .0015) and middle (P = .0179) regions of the mesial roots of mandibular molars and mesiobuccal roots of maxillary molars. Groups 2 and 3 resulted in cleaning 67.8% and 97.2% of the mesiobuccal and mesiolingual root canals of mandibular molars and the mesiobuccal canals of maxillary molars, respectively, whereas the results were similar among groups 2 and 3 in the apical and middle regions of distal roots. Groups 2 and 3 revealed significantly less debris than group 1 (P < .005).ConclusionsThe GWS showed a significantly greater cleaning capacity and reduction in residual debris within the mesiobuccal and mesiolingual canals of mandibular molars and the mesiobuccal canals of maxillary molars than those cleaned conventionally.Copyright © 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

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