• Sendy Isarel Hernández-Gaytán, Francisco Javier Díaz-Vásquez, Luis Gerardo Duran-Arenas, Malaquías López Cervantes, and Stephen J Rothenberg.
• Departamento de Salud Pública, Escuela de Medicina, Universidad Nacional Autónoma de México, Ciudad de México, México.
• Arch. Med. Res. 2017 Oct 1; 48 (7): 653-662.

Background And AimDengue Fever (DF) is a human vector-borne disease and a major public health problem worldwide. In Mexico, DF and Dengue Hemorrhagic Fever (DHF) cases have increased in recent years. The aim of this study was to identify variations in the spatial distribution of DF and DHF cases over time using space-time statistical analysis and geographic information systems.MethodsOfficial data of DF and DHF cases were obtained in 32 states from 1995-2015. Space-time scan statistics were used to determine the space-time clusters of DF and DHF cases nationwide, and a geographic information system was used to display the location of clusters.ResultsA total of 885,748 DF cases was registered of which 13.4% (n = 119,174) correspond to DHF in the 32 states from 1995-2015. The most likely cluster of DF (relative risk = 25.5) contained the states of Jalisco, Colima, and Nayarit, on the Pacific coast in 2009, and the most likely cluster of DHF (relative risk = 8.5) was in the states of Chiapas, Tabasco, Campeche, Oaxaca, Veracruz, Quintana Roo, Yucatán, Puebla, Morelos, and Guerrero principally on the Gulf coast over 2006-2015.ConclusionThe geographic distribution of DF and DHF cases has increased in recent years and cases are significantly clustered in two coastal areas (Pacific and Gulf of Mexico). This provides the basis for further investigation of risk factors as well as interventions in specific areas.Copyright © 2018 IMSS. Published by Elsevier Inc. All rights reserved.

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