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- George M Rodgers.
- Division of Hematology and Hematologic Malignancies, University of Utah Health Sciences Center, 30 North 1900 East, Salt Lake City, UT 84132, USA. Electronic address: george.rodgers@hsc.utah.edu.
- Neurosurg. Clin. N. Am. 2018 Oct 1; 29 (4): 485-492.
AbstractNormal hemostasis provides for balanced interactions between the blood vessel wall, coagulation proteins, and platelets. After vascular injury, primary hemostasis and secondary hemostasis function in a coordinated fashion to stop bleeding. Standard coagulation tests have been shown in multiple studies to predict bleeding and mortality in neurosurgical patients. Emerging coagulation tests are useful point-of-care assays that guide transfusion therapy and diagnose patients with hyperfibrinolysis. This article provides an overview of hemostasis, a summary of standard coagulation testing and point-of-care tests, and a brief review of coagulation test usefulness in neurosurgery, focusing on studies in patients with traumatic brain injury.Copyright © 2018 Elsevier Inc. All rights reserved.
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