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Randomized Controlled Trial Comparative Study Clinical Trial
Multicenter double-blind efficacy and safety study comparing alprazolam, diazepam and placebo in clinically anxious patients.
- J B Cohn.
- J Clin Psychiatry. 1981 Sep 1; 42 (9): 347-51.
AbstractBoth alprazolam and diazepam were superior to placebo for the treatment of the clinical anxiety syndrome throughout a four-week double-blind multiclinic trial in 976 outpatients. At the fourth-week evaluation of the 845 patients completing the study, the 326 patients receiving alprazolam showed significantly more improvement than the 344 patients receiving diazepam on all 4 anxiety rating scales utilized (Hamilton Anxiety Rating Scale, Physician's Global Assessment, Patient's Global Assessment, and Target Symptoms).
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