• Comput Struct Biotechnol J · Jan 2020

    Review

    Probing infectious disease by single-cell RNA sequencing: Progresses and perspectives.

    • Geyang Luo, Qian Gao, Shuye Zhang, and Bo Yan.
    • Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
    • Comput Struct Biotechnol J. 2020 Jan 1; 18: 2962-2971.

    AbstractThe increasing application of single-cell RNA sequencing (scRNA-seq) technology in life science and biomedical research has significantly increased our understanding of the cellular heterogeneities in immunology, oncology and developmental biology. This review will summarize the development of various scRNA-seq technologies; primarily discussing the application of scRNA-seq on infectious diseases, and exploring the current development, challenges, and potential applications of scRNA-seq technology in the future.© 2020 The Author(s).

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