• Jun Liu, Shuwei Liu, Xueyuan Heng, Chang Fei, Youyi Wei, Jian Zhang, Zhonghe Zhang, and Yuchun Tang.
• Department of Neurosurgery, Linyi People's Hospital of Shandong University, Jinan, Shandong, People's Republic of China.
• World Neurosurg. 2012 Nov 1;78(5):510-5.

ObjectiveThe computerized freezing milling technique is derived from the virtual human project. It has been widely used in three-dimensional (3D) reconstruction of the human body and organs. With this technique, the study was undertaken to explore the 3D features and adjacent anatomic relationships of the sellar region for skull base surgery.MethodsContinuous thin sections on the coronary plane were performed with the computerized freezing milling technique using a human head specimen. The related structures were described in six sections. After segmenting, labeling, and extracting in serial sections, the 3D reconstruction of the sellar region was finished with Amira 4.1 software.ResultsA total of 390 thin coronary sections were obtained. In six sections, the anatomic relationships of the pituitary gland, carotid artery, sphenoid sinus, and nerves are displayed. Three-dimensional images of the sellar region are video films that continuously and dynamically display anatomic structures in 3D space at different velocities. It can show that the cavernous segment of the internal carotid artery is located anterolateral to the sphenoid sinus and lateral to the pituitary gland. The optic nerve protrudes into the superolateral portion of the sphenoid sinus.ConclusionsThe combination of coronary sectional anatomy and 3D reconstruction can display the anatomic characteristics of the sellar region. The 3D models are video films that continuously and dynamically display anatomic structures in 3D space at different velocities.Copyright © 2012 Elsevier Inc. All rights reserved.

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