• Nicolas Bertholet, John A Cunningham, Mohamed Faouzi, Jacques Gaume, Gerhard Gmel, Bernard Burnand, and Jean-Bernard Daeppen.
• Alcohol Treatment Center, Department of community medicine and health, Lausanne University Hospital, Lausanne, Switzerland.
• Plos One. 2015 Jan 1; 10 (12): e0144146.

IntroductionAlcohol use is one of the leading modifiable morbidity and mortality risk factors among young adults.Study Design2 parallel-group randomized controlled trial with follow-up at 1 and 6 months.Setting/ParticipantsInternet based study in a general population sample of young men with low-risk drinking, recruited between June 2012 and February 2013. Intervention: Internet-based brief alcohol primary prevention intervention (IBI). The IBI aims at preventing an increase in alcohol use: it consists of normative feedback, feedback on consequences, calorific value alcohol, computed blood alcohol concentration, indication that the reported alcohol use is associated with no or limited risks for health. Intervention group participants received the IBI. Control group (CG) participants completed only an assessment.Main Outcome MeasuresAlcohol use (number of drinks per week), binge drinking prevalence. Analyses were conducted in 2014-2015.ResultsOf 4365 men invited to participate, 1633 did so; 896 reported low-risk drinking and were randomized (IBI: n = 451; CG: n = 445). At baseline, 1 and 6 months, the mean (SD) number of drinks/week was 2.4(2.2), 2.3(2.6), 2.5(3.0) for IBI, and 2.4(2.3), 2.8(3.7), 2.7(3.9) for CG. Binge drinking, absent at baseline, was reported by 14.4% (IBI) and 19.0% (CG) at 1 month and by 13.3% (IBI) and 13.0% (CG) at 6 months. At 1 month, beneficial intervention effects were observed on the number of drinks/week (p = 0.05). No significant differences were observed at 6 months.ConclusionWe found protective short term effects of a primary prevention IBI.Trial RegistrationControlled-Trials.com ISRCTN55991918.

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