• Am J Chinese Med · Jan 1994

    Case Reports

    A useful diagnostic method for drug-induced pneumonitis: a case report.

    • A Kawasaki, Y Mizushima, H Kunitani, M Kitagawa, and M Kobayashi.
    • First Department of Internal Medicine, Toyama Medical and Pharmaceutical University, Japan.
    • Am J Chinese Med. 1994 Jan 1; 22 (3-4): 329-36.

    AbstractA 51 year-old male was admitted to our hospital with chief complaints of fever, dry cough and dyspnea. Chest X-ray films and his history of taking Chinese medicine for liver dysfunction were suggestive of drug-induced pneumonitis. Lymphocyte stimulation test (LST) to causative Chinese medical drugs of Sho-saiko-to and Dai-saiko-to was negative with peripheral blood lymphocytes (PBL), but was positive with lymphocytes from bronchoalveolar lavage fluid (BALF). In vivo challenge test for Sho-saiko-to was positive. The LST with BALF-lymphocytes proved to be very useful in making a diagnosis of drug-induced pneumonitis.

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