• Int. J. Clin. Pract. · Aug 2021

    Evaluation of non-invasive arterial stiffness parameters and their relationship with physical activity, anthropometric indices and lipid profiles in healthy middle-aged adults: results of the PERSIAN cohort study.

    • Mohammad Nosrati-Oskouie, Sajjad Arefinia, Eslami Hasan AbadiSaeedSDepartment of Medical Informatics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Abdolreza Norouzy, Hamed Khedmatgozar, Nazanin Sadat Aghili-Moghaddam, Maryam Alinezhad-Namaghi, Mohammad Reza Shadmand Foumani Moghadam, and Reza Rezvani.
    • Department of Clinical Nutrition and Dietetics, Faculty of Nutrition Sciences and Food Technology, Tabriz University of Medical Sciences, Tabriz, Iran.
    • Int. J. Clin. Pract. 2021 Aug 1; 75 (8): e14275.

    BackgroundArterial stiffness (AS) indicates the initial stage of cardiovascular disease (CVD), which is associated with modifiable and lifestyle risk factors. We aimed to examine the association of AS with anthropometric indices, lipid profiles and physical activity (PA).MethodsSix hundred and fifty-eight healthy middle-aged adults were selected and anthropometric indices [body mass index, waist circumferences (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), neck circumferences, a body shape index (ABSI), body roundness index (BRI), body fat mass (BFM), visceral fat area, fat-free mass (FFM), lipid profiles and PA] were measured. AS is measured by carotid-femoral pulse wave velocity (cf-PWV) and central augmentation index (cAIx).ResultsOur results show that cf-PWV was positively associated with TGs (β = 0.10, P = .01) and anthropometric indices correlated with WC (β = 0.11, P = .02), WHR (β = 0.09, P = .03), WHtR (β = 0.1, P = .02) and BRI (β = 0.09, P = .04). cAIx was independently positively associated with cholesterol (β = 0.08, P = .03), WC (β = 0.1, P = .03), WHR (β = 0.09, P = .02), ABSI (β = 0.09, P = .01), BRI (β = 0.08, P = .05), visceral fat area (β = 0.09, P = .03) and BFM (β = 0.08, P = .04) and negatively associated with PA (β = -0.08, P = .03).ConclusionsWC, WHR and BRI were associated with both cf-PWV and cAIx. TGs and WHtR were associated with cf-PWV, while cAIx was associated with ABSI, improving these indices may be helpful to prevent CVD.© 2021 John Wiley & Sons Ltd.

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