• World Neurosurg · Nov 2012

    Case Reports

    Skull vault destruction after rhinocerebral mucormycosis.

    • Stephen Honeybul and David Anthony Morrison.
    • Department of Neurosurgery, Sir Charles Gairdner Hospital, Nedlands and Royal Perth Hospital, Perth, Western Australia, Australia. stephen.honeybul@health.wa.gov.au
    • World Neurosurg. 2012 Nov 1;78(5):553.e1-4.

    BackgroundMucormycosis is a relatively rare form of fungal infection that can be rapidly progressive. Clinical presentation depends on the anatomic area of involvement; however, the commonest form is that of rhinocerebral.Case DescriptionThis is the first case of extensive and progressive destruction of the skull vault despite antifungal therapy. The patient required aggressive surgical resection to arrest the disease progression and complex reconstruction using a custom made titanium cranioplasty.ConclusionsThis report highlights the need for early aggressive resection for cases of mucormycosis infection where there is bony involvement.Crown Copyright © 2012. Published by Elsevier Inc. All rights reserved.

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