• Yuichi Sato, Tsukasa Wada, Yasumasa Nishikawa, Kenji Yoshida, Akira Kurose, Akira Ogawa, and Kuniaki Ogasawara.
• Department of Neurosurgery, Iwate Medical University, Morioka, Japan.
• World Neurosurg. 2013 Sep 1;80(3-4):436.e11-3.

BackgroundWe report a case of an uncommon association of pituitary adenoma with neuronal choristoma that usually is diagnosed at initial surgery.Case DescriptionA 50-year-old woman with acromegaly and bitemporal hemianopsia underwent removal of a pituitary adenoma via the transsphenoidal approach. Histologic examination of the first surgical specimen demonstrated only adenoma, which was eosinophilic and expressed growth hormone. Fourteen years later, bitemporal hemianopsia recurred, and magnetic resonance imaging revealed regrowth of the residual tumor.DiscussionThe patient underwent removal of the regrown tumor via the transsphenoidal approach. Histologic examination of the second surgical specimen revealed gangliocytoma and a small component of pituitary adenoma.ConclusionsThe present case report supports the theory that pituitary adenoma with neuronal choristoma might represent the result of neuronal differentiation from pituitary adenoma.Copyright © 2013. Published by Elsevier Inc.

38 keywords...

hide…