• Arch. Gynecol. Obstet. · Nov 2011

    Case Reports

    Cannabinoid hyperemesis syndrome: an underreported entity causing nausea and vomiting of pregnancy.

    • Seraina M Schmid, Olav Lapaire, Dorothy J Huang, Frank Edwin Jürgens, and Uwe Güth.
    • Department of Gynecology and Obstetrics, University Hospital Basel (UHB), Spitalstrasse 21, 4031 Basel, Switzerland.
    • Arch. Gynecol. Obstet. 2011 Nov 1; 284 (5): 1095-7.

    IntroductionIn the western world, cannabis is the most widely used drug of abuse. Cannabinoid hyperemesis syndrome, which seems to be a rare paradoxical reaction in individuals with a particular predisposition, is characterized by cyclic severe nausea and vomiting in long-term cannabis users. While the symptoms are unresponsive to antiemetic drugs, compulsive hot baths result in a considerable symptom relief.MethodsWe report the first case of cannabinoid hyperemesis syndrome in pregnancy. A 26-year-old patient was admitted to our clinic in the 10th week of gestation.ConclusionBefore undertaking time-consuming and expensive medical examinations to rule out other medical reasons for therapy-resistant hyperemesis in pregnancy, obstetricians should determine whether compulsive bathing or showering provides symptomatic relief and ask specific questions regarding possible/suspected cannabis consumption.

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