• World Neurosurg · Jul 2021

    Case Reports

    Diffuse Paget's disease of the skull with intense uptake of Technetium-99m-labelled diphosphonate tracer in bone scintigraphy.

    • Daniel W Griepp, Abin Sajan, and Maziar Sighary.
    • College of Osteopathic Medicine, New York Institute of Technology, Old Westbury, New York, USA; Department of Radiology, SUNY Downstate Health Sciences University, Brooklyn, New York, USA.
    • World Neurosurg. 2021 Jul 1; 151: 89-90.

    AbstractImaging in patients with Paget's disease of bone is very important clinically to show the presence of Pagetic abnormalities, assess disease progression, and identify adversely affected structures throughout disease course. Abnormalities and progression may be seen on radiographs, computed tomography, magnetic resonance imaging, and nuclear imaging. Herein, we report a case Paget's disease of bone showing diffuse characteristic pathology using technetium-99m-labelled diphosphonate tracer in bone scintigraphy (nuclear imaging). This case emphasizes the ability of nuclear imaging to rapidly visualize and assess progressive distribution of Pagetic involvement in a patient previously diagnosed with pituitary adenoma and mild Paget's disease of the skull.Copyright © 2021 Elsevier Inc. All rights reserved.

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