• American heart journal · Apr 2019

    Early initiation of extracorporeal life support in refractory out-of-hospital cardiac arrest: Design and rationale of the INCEPTION trial.

    • Martine E Bol, Martje M Suverein, Roberto Lorusso, Delnoij Thijs S R TSR Department of Intensive Care, Maastricht University Medical Center, Maastricht, The Netherlands; Department of Cardiology, Maastricht University Med, George J Brandon Bravo Bruinsma, Luuk Otterspoor, Marijn Kuijpers, Ka Yan Lam, Vlaar Alexander P J APJ Department of Intensive Care, Amsterdam University Medical Center location AMC, Amsterdam, The Netherlands., Carlos V Elzo Kraemer, Joris J van der Heijden, Erik Scholten, Driessen Antoine H G AHG Heart Center, Department of Cardiothoracic Surgery, Amsterdam University Medical Center location AMC, Amsterdam, The Netherlands., José M Montero Cabezas, Saskia Z H Rittersma, Bram G Heijnen, Fabio S Taccone, Brigitte Essers, Tammo Delhaas, Patrick W Weerwind, Roekaerts Paul M H J PMHJ Department of Intensive Care, Maastricht University Medical Center, Maastricht, The Netherlands; CARIM, School for Cardiovascular Diseases, Maas, Jos G Maessen, and van de Poll Marcel C G MCG Department of Intensive Care, Maastricht University Medical Center, Maastricht, The Netherlands; NUTRIM, School for Nutrition and Translational.
    • Department of Intensive Care, Maastricht University Medical Center, Maastricht, The Netherlands; NUTRIM, School for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, The Netherlands.
    • Am. Heart J. 2019 Apr 1; 210: 58-68.

    AbstractReturn of spontaneous circulation occurs in less than 10% of patients with cardiac arrest undergoing cardiopulmonary resuscitation (CPR) for more than 15 minutes. Studies suggest that extracorporeal life support during cardiopulmonary resuscitation (ECPR) improves survival rate in these patients. These studies, however, are hampered by their non-randomized, observational design and are mostly single-center. A multicenter, randomized controlled trial is urgently warranted to evaluate the effectiveness of ECPR.Copyright © 2018 The Author(s). Published by Elsevier Inc. All rights reserved.

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