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- Shino Nehashi, Rie Kato, and Jiro Sato.
- Department of Anesthesiology, Tokyo Women's Medical University Yachiyo Medical Center, Yachiyo 276-8524.
- Masui. 2009 Jan 1; 58 (1): 25-33.
AbstractMen and women have different body compositions such as fat and fluid, and hormonal environments which affect both pharmacokinetics and pharmacodynamics of anesthesia-related drugs. The knowledge on gender differences in the effects of these drugs has been accumulated. We firstly focus on gender differences in the depth of anesthesia, intraoperative awareness and emergence from anesthesia. Then, gender differences in the effects of commonly used anesthesia-related agents are discussed. Although there have not been remarkable differences demonstrated, better understanding of the difference may lead to satisfying perioperative anesthetic cares for each sex.
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