• Pacing Clin Electrophysiol · Mar 2003

    Case Reports

    Torsades de pointes and QT prolongation due to a combination of loratadine and amiodarone.

    • Shaul Atar, Nahum A Freedberg, Dante Antonelli, and Tiberio Rosenfeld.
    • Department of Cardiology, Ha'Emek Medical Center, Afula 18101, Israel. atar_sh@clalit.org.il
    • Pacing Clin Electrophysiol. 2003 Mar 1; 26 (3): 785-6.

    AbstractTorsades de pointes (TdP) has not been previously reported with loratadine. A 73-year old woman on chronic treatment with amiodarone for atrial fibrillation received loratadine and presented with syncope and multiple episodes of TdP. We suggest that QT interval should be monitored whenever loratadine is co-administered with drugs that may potentially prolong QT.

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