• Respiratory investigation · May 2021

    Case Reports

    Sustained coronavirus disease 2019-related organizing pneumonia successfully treated with corticosteroid.

    • Hiroshi Takumida, Shinyu Izumi, Keita Sakamoto, Masao Hashimoto, Satoru Ishii, Manabu Suzuki, Jin Takasaki, Mariko Tanaka, Toru Igari, and Masayuki Hojo.
    • Department of Respiratory Medicine, Center Hospital of the National Center for Global Health and Medicine, Tokyo, Japan. Electronic address: htakumida@hosp.ncgm.go.jp.
    • Respir Investig. 2021 May 1; 59 (3): 377-381.

    AbstractA 70-year-old Japanese man contracted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and required oxygen to maintain oxygen saturation (>90%), 5 weeks after onset of coronavirus disease 2019 (COVID-19) symptoms. Transbronchial lung cryobiopsy revealed pathological features of organizing pneumonia with alveolar epithelial injury, and prednisolone administration led to alleviation of respiratory symptoms and recovery of respiratory function. This case report is the first to demonstrate the use of corticosteroids to successfully treat post-COVID-19 respiratory failure in a patient with biopsy-proven organizing pneumonia. We propose that steroid treatment be considered for patients with persistent respiratory dysfunction as COVID-19 pneumonia sequelae.Copyright © 2021 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.

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