• Zheng Cai Lou.
• Department of Otorhinolaryngology, the affiliated Yiwu hospital of Wenzhou medical university (Yiwu central Hospital), 699 jiangdong road, Yiwu city, 322000, Zhejiang provice, China. louzhengcai@163.com.
• J Otolaryngol Head N. 2020 Jun 22; 49 (1): 40.

ObjectiveTo compare surgical results of endoscopic myringoplasty using double layer cartilage-perichondrium grafts versus single fascia grafts.Study DesignProspective, randomized, controlled.SettingUniversity-affiliated teaching hospital.Subjects And MethodsIn total,134 patients who underwent endoscopic myringoplasty were included in this study. Patients in group A received a double layer tragal cartilage-perichondrium graft and those in group B received a temporal muscle fascia graft. The groups were compared with respect to the pre- and postoperative air-bone gap (ABG) and the graft success rate.ResultsThe graft success rate was 98.5% (66/67) in the Group A and 94.0% (63/67) in the Group B at 6 months, the difference wasn't statistically significant (p = 0.362). However, the graft success rate was 97.0% (65/67) in the Group A and 85.1% (57/67) in the Group B at 12 months, the difference was statistically significant (p = 0.034). In addition, only one patient (1.49%) had small keratin pearls in the Group A, no patients developed cholesteatoma of middle ear in either group.ConclusionsThe endoscopic double layer perichondrium-cartilage graft technique is feasible for repairing medium or larger perforations, it has a better long-term graft success rate and less operative time compared with the single layer fascia graft technique. However, long-term hearing outcomes were the same for the single and double layer closure techniques.

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