• İsmail Özler, Hale Aydin, Onur Can Güler, Esen BostancıIşılIRadiology Clinics of University of Health Sciences, Ankara Oncology Education and Research Hospital, Ankara, Turkey., Şahin GünerBaharBRadiology Clinics of University of Health Sciences, Ankara Oncology Education and Research Hospital, Ankara, Turkey., Niyazi Karaman, Lütfi Doğan, and Cihangir Özaslan.
• General Surgery Clinics of University of Health Sciences, Ankara Oncology Education and Research Hospital, Ankara, Turkey.
• Int. J. Clin. Pract. 2021 Aug 1; 75 (8): e14332.

AimThe aim of this study was to assess the efficacy of preoperative axillary ultrasonography (AUS) and preoperative axillary fine-needle aspiration biopsy (FNAB) from suspicious lymph nodes in clinically node-negative breast cancer to compare with radiologically positive and sentinel lymph node biopsy (SLNB) positive involvement.MethodClinically node-negative early-stage breast cancer patients were included in the study. These patients underwent preoperative AUS examination, suspicious lymph nodes were evaluated with FNAB. AUS-FNAB results were compared with those of SLNB or axillary dissection.ResultsOf 181 patients undergoing AUS, 32 were reported to have axillary metastasis, 25 suspicious, and 124 benign nodes. The suspicious group underwent FNAB examination and metastasis was found in 9 of them. The sensitivity of AUS-FNAB was found to be 64.06%, specificity 100%, positive predictive value 100%, and negative predictive value (NPV) 83.5%. The false negativity rate (FN) of this method was 16,4%. Lymphovascular invasion and tumour size were found statistically significant factors for false negativity.ConclusionIt was concluded that axillary AUS-FNAB with its high NPV, low FN rate, may be a clinical alternative to SLNB for early-stage breast cancer patients.© 2021 John Wiley & Sons Ltd.

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