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- D Tzoanopoulos, D Stakos, D Hatseras, K Ritis, and G Kartalis.
- First Department of Internal Medicine, Democritus University of Thrace, Regional Hospital of Alexandroupolis, 68 100, Alexandroupolis, Greece. tzoanop@otenet.gr
- Neth J Med. 2001 Oct 1; 59 (4): 177-80.
AbstractDefinitive diagnosis of tuberculous pericarditis requires identification of bacilli in pericardial fluid or tissue. Conventional diagnostic methods are time-consuming and have a low sensitivity making bacteriological confirmation of the disease very difficult. Hereby, we report the case of molecular detection of Mycobacterium tuberculosis in pericardial fluid, bone marrow and peripheral blood from a 63-year-old woman with pericardial tuberculosis, using a nested PCR assay specific for IS6110 insertion element of M. tuberculosis complex. The patient had an excellent response to a three-drug combination anti-tuberculous regimen and 1 year later was asymptomatic, without evidence of constrictive pericarditis.
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