• J Cardiovasc Surg · Mar 1988

    Randomized Controlled Trial Comparative Study Clinical Trial

    PTFE versus human umbilical vein in above knee femoro-popliteal bypass. Early results of a randomized clinical trial.

    • G J Aalders, T J van Vroonhoven, H J Lobach, and C C Wijffels.
    • Department of Surgery, St. Elisabeth Hospital, Tilburg, The Netherlands.
    • J Cardiovasc Surg. 1988 Mar 1; 29 (2): 186-90.

    AbstractThe results of a prospective randomized clinical trial comparing PTFE and HUV grafts in above knee femoro-popliteal reconstruction are presented. A total of 93 limbs were randomized, three patients died in the early postoperative period, leaving 90 (45 PTFE and 45 HUV bypasses) to be analysed. During 18 months of follow-up only 3 HUV grafts occluded in contrast to 15 occluded PTFE grafts. After one year patency rates for HUV were 90% versus 67% for PTFE grafts, after 18 months 86% and 63% respectively. From one year postoperatively onwards these results are statistically and significantly different. When an above knee femoro-popliteal reconstruction is performed and autologous vein is not available or purposely not used, HUV gives better results than PTFE and is the graft of choice.

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