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Case Reports
Danaparoid for cardiopulmonary bypass in patients with previous heparin-induced thrombocytopenia.
- S Gillis, G Merin, D Zahger, M Deeb, B Drenger, E Hyam, and A Eldor.
- Department of Haematology, Hadassah University Medical Centre, Ein Karem, Jerusalem, Israel.
- Br. J. Haematol. 1997 Sep 1; 98 (3): 657-9.
AbstractAnticoagulation for cardiopulmonary bypass in patients with heparin-induced thrombocytopenia requires the use of other anticoagulants. We report a case in whom this was achieved using the heparinoid danaparoid (Orgaran). Based on our experience and a review of the literature, we provide guidelines for managing these rare patients. A danaparoid dose substantially lower than that recommended by the manufacturer may minimize bleeding complications.
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