• Diagn. Microbiol. Infect. Dis. · Aug 2018

    Clinical Impact of a Rapid Streptococcal Antigen Test on Antibiotic Use in Adult Patients.

    • Monique Dodd, Allen Adolphe, Alisha Parada, Meghan Brett, Karissa Culbreath, and Renée-Claude Mercier.
    • University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America; TriCore Reference Laboratories, Albuquerque, New Mexico, United States of America.
    • Diagn. Microbiol. Infect. Dis. 2018 Aug 1; 91 (4): 339-344.

    IntroductionAdult pharyngitis is rarely attributable to group A streptococci. Utilization of a rapid streptococcal antigen test (RADT) may improve appropriate prescribing for bacterial pharyngitis.MethodsClinic 1 performed RADTs with subsequent Group A DNA probe test (GADNA) from November 2014-March 2015 and November 2015-March 2016 while Clinic 2 was the control clinic, then implemented the RADT with a GADNA from November 2015-March 2016. All GADNA results were obtained for each clinic from October 2013-March 2016.ResultsAt Clinic 1, 22.2% versus 8.5% of patients received inappropriately prescribed antibiotics for a GADNA or RADT result, respectively (p=0.048). For Clinic 2, 51.1% compared to 21.4% of patients were inappropriately prescribed antibiotic for a GADNA or RADT result, respectively (p=0.038). Overall, the total GADNA without RADT testing or RADTs with subsequent GADNA testing, 41.6% versus 11% of patients were inappropriately prescribed antibiotics, respectively (p=<0.0001).ConclusionUtilizing the RADT prevented unnecessary prescribing of antibiotics in adults.Copyright © 2018 Elsevier Inc. All rights reserved.

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