• Masayuki Someya, Jun Sasahara, Satoshi Yamamoto, Akihisa Sawada, Masanori Nishikawa, and Keisuke Ishii.
• Department of Maternal Fetal Medicine, Osaka Women's and Children's Hospital, Osaka, Japan.
• J. Obstet. Gynaecol. Res. 2019 Dec 1; 45 (12): 2456-2460.

AbstractCongenital hemangioma is a rare vascular tumor that develops prenatally, and a large congenital hemangioma may be accompanied by the Kasabach-Merritt phenomenon. We present a case of prenatally diagnosed fetal congenital hemangioma through ultrasound and maternal anti-Jr(a) antibody alloimmunization with elevated middle cerebral artery peak systolic velocity. To investigate fetal anemia and hemostatic condition, we performed percutaneous umbilical blood sampling, which revealed no symptom of either Kasabach-Merritt phenomenon or sensitization to anti-Jr(a) antibody. Consequently, pregnancy could be continued without further intervention. After birth, congenital hemangioma was found on the infant's left thigh, and Kasabach-Merritt phenomenon was not shown. Percutaneous umbilical blood sampling could provide precise information prenatally in case of congenital hemangioma with maternal alloimmunization.© 2019 Japan Society of Obstetrics and Gynecology.

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