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- D S Chattergoon, M A McGuigan, G Koren, P Hwang, and S Ito.
- Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, Ontario, Canada.
- Neurology. 1997 Nov 1; 49 (5): 1442-4.
AbstractTwo children developed multiorgan dysfunction with disseminated intravascular coagulation 9 days after lamotrigine was added to their antiepileptic therapy, which included valproic acid. During the episodes, rhabdomyolysis was detected in one of them, while being seizure-free, suggesting that this adverse reaction may involve muscular tissue.
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