• Am J Psychiatry · Jan 2018

    Meta Analysis

    Dissociation in Psychiatric Disorders: A Meta-Analysis of Studies Using the Dissociative Experiences Scale.

    • Lisa Lyssenko, Christian Schmahl, Laura Bockhacker, Ruben Vonderlin, Martin Bohus, and Nikolaus Kleindienst.
    • From the Institute for Psychiatric and Psychosomatic Psychotherapy, Central Institute of Mental Health, Mannheim, Germany; the Department of Psychosomatic Medicine and Psychotherapy, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; the Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, Ontario; and the Department of Health, Antwerp University, Antwerp, Belgium.
    • Am J Psychiatry. 2018 Jan 1; 175 (1): 37-46.

    ObjectiveDissociation is a complex, ubiquitous construct in psychopathology. Symptoms of dissociation are present in a variety of mental disorders and have been connected to higher burden of illness and poorer treatment response, and not only in disorders with high levels of dissociation. This meta-analysis offers a systematic and evidence-based study of the prevalence and distribution of dissociation, as assessed by the Dissociative Experiences Scale, within different categories of mental disorders, and it updates an earlier meta-analysis.MethodMore than 1,900 original publications were screened, and 216 were included in the meta-analysis, comprising 15,219 individuals in 19 diagnostic categories.ResultsThe largest mean dissociation scores were found in dissociative disorders (mean scores >35), followed by posttraumatic stress disorder, borderline personality disorder, and conversion disorder (mean scores >25). Somatic symptom disorder, substance-related and addictive disorders, feeding and eating disorders, schizophrenia, anxiety disorder, OCD, and most affective disorders also showed mean dissociation scores >15. Bipolar disorders yielded the lowest dissociation scores (mean score, 14.8).ConclusionsThe findings underline the importance of careful psychopathological assessment of dissociative symptoms in the entire range of mental disorders.

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