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Case Reports
First case of convalescent plasma transfusion in a child with COVID-19-associated severe aplastic anemia.
- Magdalena Figlerowicz, Anna Mania, Karol Lubarski, Zuzanna Lewandowska, Wojciech Służewski, Katarzyna Derwich, Jacek Wachowiak, and Katarzyna Mazur-Melewska.
- Department of Infectious Diseases and Child Neurology, Poznan University of Medical Sciences, Szpitalna 27/33, 60-572 Poznań, Poland. Electronic address: mfiglerowicz@gmail.com.
- Transfus Apher Sci. 2020 Oct 1; 59 (5): 102866.
AbstractWe present the case of a six-year-old girl with severe COVID-19, in whom SARS-CoV-2 was successfully eliminated after convalescent plasma transfusion. Children show a variable clinical course of COVID-19, from asymptomatic to critical. In our patient, we diagnosed COVID-19-associated aplastic anemia with severe pancytopenia. The correlation between SARS-CoV-2 infection with aplastic anemia remains unclear. At the beginning of the disease, we used antiviral drugs and immune modulators as therapy but without any positive results. After providing a transfusion of convalescent plasma, the elimination of SARS-CoV-2 was observed. We did not observe any adverse events of this treatment. The girl still has a diagnosis of aplastic anemia and requires specialist therapy.Copyright © 2020 Elsevier Ltd. All rights reserved.
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