• J. Neurol. Sci. · Aug 2004

    Review

    Mechanisms of mitoxantrone in multiple sclerosis--what is known?

    • Oliver Neuhaus, Bernd C Kieseier, and Hans-Peter Hartung.
    • Department of Neurology, Heinrich Heine University, Moorenstrasse 5, D-40225 Düsseldorf, Germany. oliver.neuhaus@uni-duesseldorf.de
    • J. Neurol. Sci. 2004 Aug 15; 223 (1): 25-7.

    AbstractThe recent publication of the MIMS-study (Mitoxantrone In Multiple Sclerosis) and the approval of several health authorities support the use of mitoxantrone in patients with active relapsing-remitting or secondary progressive multiple sclerosis. This review provides information on data thus far present on the putative mechanisms of action of mitoxantrone in the immunopathogenesis of this disabling disease.Copyright 2004 Elsevier B.V.

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