• J. Cell. Biochem. · Nov 2005

    Review

    Advances in understanding bone cancer pain.

    • M J Goblirsch, P Zwolak, and D R Clohisy.
    • University of Minnesota, Minneapolis, Minnesota, USA.
    • J. Cell. Biochem. 2005 Nov 1; 96 (4): 682-8.

    AbstractExperimental animal models of bone cancer pain have emerged and findings have provided a unique glimpse into unraveling the mechanism that drives this debilitating condition. Key contributors to the generation and maintenance of bone cancer pain are tumor-induced osteolysis, tumor itself, and production of nociceptive mediators in the bone-tumor microenvironment.Copyright 2005 Wiley-Liss, Inc.

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