• J. Am. Acad. Dermatol. · May 2000

    Case Reports

    Scleromyxedema with dermato-neuro syndrome.

    • J Gonzalez, M Palangio, J Schwartz, A S Klainer, and E Bisaccia.
    • Section of Photopheresis and Department of Internal Medicine, Morristown Memorial Hospital, Morristown, NJ 07962-1956, USA.
    • J. Am. Acad. Dermatol. 2000 May 1; 42 (5 Pt 2): 927-8.

    AbstractScleromyxedema is a rare connective tissue disease of unknown cause characterized by a generalized papular eruption, dermal fibroblast proliferation, and monoclonal paraproteinemia. A paroxysmal triad consisting of high fever, seizures, and coma with a flu-like prodrome can rarely occur in patients with scleromyxedema and is termed "dermato-neuro syndrome." We describe a 41-year-old patient with scleromyxedema in whom the dermato-neuro syndrome developed.

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