• Interdiscip Neurosurg · Dec 2020

    Encephalitis associated with the SARS-CoV-2 virus: A case report.

    • Fenne Vandervorst, Kaat Guldolf, Ilse Peeters, Tim Vanderhasselt, Kathleen Michiels, Kinge Johanna Berends, Johan Van Laethem, Lissa Pipeleers, Stefanie Vincken, Laura Seynaeve, and Sebastiaan Engelborghs.
    • Department of Neurology, UZ Brussel and Center for Neurosciences (C4N), Vrije Universiteit Brussel, Belgium.
    • Interdiscip Neurosurg. 2020 Dec 1; 22: 100821.

    AbstractThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) usually causes fever, respiratory symptoms, malaise and myalgia. Recent observations suggested possible neurological complications of COVID-19, including the first report of suspected viral encephalitis. We report a case of a 29-year-old male with -on nasopharyngeal testing- confirmed SARS-CoV-2 infection with severe respiratory symptoms, followed by clinical and radiological signs of encephalitis. Magnetic resonance imaging (MRI) of the brain showed an asymmetric FLAIR-hyperintensity of the left medial temporal cortex associated with mild gyral expansion. Lumbar puncture was normal and PCR's for SARS-CoV-2 virus on CSF were negative. Clinicians treating SARS-CoV-2 infected patients should be aware of possible neurological complications, like encephalitis. The diagnosis of SARS-CoV-2 encephalitis is difficult as CSF analysis may be normal.© 2020 Published by Elsevier B.V.

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