• Pediatr. Infect. Dis. J. · Jan 2012

    Decreased innate immune cytokine responses correlate with disease severity in children with respiratory syncytial virus and human rhinovirus bronchiolitis.

    • Carla García, Alejandra Soriano-Fallas, Juanita Lozano, Nora Leos, Ana M Gomez, Octavio Ramilo, and Asuncion Mejias.
    • Division of Pediatric Infectious Diseases, UT Southwestern Medical Center, Dallas, TX, USA.
    • Pediatr. Infect. Dis. J. 2012 Jan 1; 31 (1): 86-9.

    AbstractThe immunopathogenesis of respiratory syncytial virus (RSV) and human rhinovirus lower respiratory tract infections in children remains to be defined. We measured nasal wash concentrations of 29 cytokines in infants with RSV or human rhinovirus lower respiratory tract infections. Concentrations of interferon-γ in RSV and innate immunity cytokines in both infections inversely correlated with disease severity.

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