• Yingyu Liu, Jinzi Chen, Zimei Dong, Guangwen Chen, and Dezeng Liu.
• College of Life Science, Henan Normal University, Xinxiang, China.
• Biomarkers. 2021 Feb 1; 26 (1): 55-64.

PurposeTo verify antioxidant responses and lipid peroxidation can be used as sensitive indicators for the risk assessment of the Wei River.Material And MethodsWe investigate the effects of the Wei River on oxidative stress of planarian Dugesia japonica by antioxidant parameters, and use ICP-MS to measure the heavy metals in the Wei River. Then, we observe the effects of three common heavy metal ions (Cr3+, Hg2+, Pb2+) on the regeneration of planarians on morphological and histological levels.ResultsThe significant changes of antioxidant parameters (SOD, CAT, GPx, GST, T-AOC) and MDA content indicate that oxidative stress is induced after the Wei River exposure on planarians, though the heavy metals in the Wei River are not exceeding the standards. Then, the regeneration of planarians shows different degree of morphological and histological damage after Cr3+, Hg2+ and Pb2+ exposure.ConclusionWe speculate that the heavy metal ions in the Wei River, especially Cr3+, Hg2+ and Pb2+, may give rise to oxidative damage on planarians. These findings illustrate that planarian can serve as an indicator of aquatic ecosystem pollution, antioxidant responses and lipid peroxidation can also be used as sensitive indicators and provide an excellent opportunity for urban river risk assessment.

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