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Am J Rhinol Allergy · Sep 2020
Multicenter StudyPrevalence and Recovery From Olfactory and Gustatory Dysfunctions in Covid-19 Infection: A Prospective Multicenter Study.
- Eléonore Chary, Florent Carsuzaa, Jean-Paul Trijolet, Anne-Laure Capitaine, Mariam Roncato-Saberan, Kevin Fouet, France Cazenave-Roblot, Mélanie Catroux, Caroline Allix-Beguec, and Xavier Dufour.
- ORL-Head and Neck Surgery, University Hospital of Poitiers, Poitiers, France.
- Am J Rhinol Allergy. 2020 Sep 1; 34 (5): 686-693.
BackgroundCovid-19 is defined by an association of multiple symptoms, including frequently reported olfactory and gustatory disorders.ObjectiveThe main purpose of this study was to analyze the prevalence of these neurosensory impairments in patients with Covid-19, and to assess short-term recovery.MethodsWe performed a multicenter case series study during the Covid-19 epidemic. All patients presenting a RT-PCR-confirmed SARS-CoV-2 infection were included, whether hospitalized or treated at home. To analyze the prevalence and features of olfactory and gustatory dysfunctions, a phone interview was conducted 5 days after the positive PCR result. The questionnaire was submitted again 10 days later to patients having reported olfactory and gustatory disorders, in order to assess their recovery.Results115 patients were included in our study. 81 patients (70%) reported olfactory and gustatory disorders without nasal obstruction or rhinorrhea. These impairments were more frequently reported in the female population, young people, and house-bound patients with mild symptomatic forms. Short-term recovery assessed at Day 15 was complete for 64% of the patients, and incomplete in 33%. Median recovery time was 15 days (4-27 days) after olfactory or gustatory symptom onset.ConclusionOlfactory and gustatory dysfunctions related to Covid-19 are frequently reported and prevalent in mild symptomatic forms of the disease. Recovery in most cases seems rapid and complete.
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