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- Sacha Stelzer-Braid, Gregory J Walker, Anupriya Aggarwal, Sonia R Isaacs, Malinna Yeang, Zin Naing, Alberto Ospina Stella, Stuart G Turville, and William D Rawlinson.
- Virology Research Laboratory, Serology and Virology Division (SAViD), Prince of Wales Hospital, Sydney, NSW, Australia; School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia. Electronic address: s.stelzer-braid@unsw.edu.au.
- Pathology. 2020 Dec 1; 52 (7): 760-763.
AbstractIsolation of the new pandemic virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential for diagnostic and research purposes including assessment of novel therapeutics. Several primary and continuous cell lines are currently used, and new organoid and engineered cell lines are being developed for improved investigation and understanding of the human immune response to this virus. Here we review the growth of SARS-CoV-2 in reference standard cell lines, engineered cell lines and new developments in this field.Copyright © 2020. Published by Elsevier B.V.
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