• The Journal of infection · Jul 1997

    Case Reports

    A case of recurrent Candida parapsilosis prosthetic valve endocarditis: cure by medical treatment alone.

    • T Lejko-Zupanc and M Kozelj.
    • Department of Infectious Diseases, Medical Centre Ljubljana, Slovenia.
    • J. Infect. 1997 Jul 1; 35 (1): 81-2.

    AbstractA patient with recurrent fungal endocarditis on prosthetic mitral valve is presented. Candida parapsilosis was the causative agent. The patient was treated medically with conventional amphotericin during the first episode. When the disease recurred conventional amphotericin B was used again, but had to be stopped because of severe side effects. Treatment was continued with amphotericin B colloidal dispersion, followed by fluconazole for 8 months. The patient is healthy 16 months after discontinuation of fluconazole. Medical treatment of fungal endocarditis on prosthetic valves can be successful in selected cases.

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