• Miki Yokokawa, Eric Good, Thomas Crawford, Aman Chugh, Frank Pelosi, Rakesh Latchamsetty, Hakan Oral, Fred Morady, and Frank Bogun.
• Division of Cardiovascular Medicine, Cardiovascular Center, University of Michigan, Ann Arbor, MI 48109-5853, USA.
• Heart Rhythm. 2012 Jun 1; 9 (6): 938-42.

BackgroundPostinfarction ventricular tachycardia (VT) typically involves the left ventricular endocardium. Right ventricular involvement in the arrhythmogenic substrate of postinfarction VT is considered unusual.ObjectiveTo assess the role of right ventricular mapping and ablation in patients with prior septal myocardial infarction.MethodsFrom among 37 consecutive patients with recurrent postinfarction VT, 18 patients with evidence of left ventricular septal involvement of myocardial infarction were identified; these patients were the subjects of this report. In these 18 patients, 166 VTs (cycle length 372 ± 117 ms) were induced. Right ventricular voltage mapping was performed in all 18 patients with left ventricular septal myocardial infarction.ResultsRight ventricular voltage mapping showed areas of low voltage in 11 patients; pace mapping from these areas revealed matching pace maps for 17 VTs, and radiofrequency ablation from the right ventricular endocardium but not the left ventricular endocardium eliminated 14 of 17 VTs. VTs with critical components in the right ventricle had a left bundle branch block morphology that had similar characteristics as left bundle branch block VTs with critical areas involving the left ventricular septum. Patients with right ventricular VT breakthrough sites had a lower ejection fraction than did patients without VT breaking out on the right ventricular septum (18% ± 5% vs 33% ± 15%; P = .01).ConclusionsRight ventricular mapping and ablation may be necessary in order to eliminate all inducible VTs in patients with postinfarction VT. More than half the patients with septal myocardial infarction have right ventricular septal areas that are critical for postinfarction VT and that cannot be eliminated by left ventricular ablation alone.Copyright © 2012 Heart Rhythm Society. All rights reserved.

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