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- Taiji Koyama, Yohei Funakoshi, Yoshinori Imamura, Sho Nishimura, Yoshimi Fujishima, Masanori Toyoda, Naomi Kiyota, Hirokazu Tanino, and Hironobu Minami.
- Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Hospital and Graduate School of Medicine, Japan.
- Intern. Med. 2021 Nov 1; 60 (21): 3485-3488.
AbstractTreatment with anti-programmed cell death-1 (PD-1) antibodies improves the anti-cancer immune response and can provide a meaningful clinical benefit to cancer patients. However, this treatment can result in specific autoimmune toxicities, termed immune-related adverse events (irAEs). Although irAEs are well recognized, the development of infectious diseases due to this treatment is not often observed. Some recent reports have indicated that patients who receive anti-PD-1 antibodies are at a higher risk for tuberculosis than others. However, reports on nontuberculous mycobacterial infection during anti-PD-1 antibody treatment are still rare. We herein report the first case of Mycobacterium mageritense infection during anti-PD-1 antibody treatment.
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