• Braz J Infect Dis · Jan 2021

    Case Reports

    Organizing pneumonia: A late phase complication of COVID-19 responding dramatically to corticosteroids.

    • Cilomar Martins de Oliveira Filho, Tarsila Vieceli, Caroline de Fraga Bassotto, João Pedro da Rosa Barbato, Tiago Severo Garcia, and Rafael Selbach Scheffel.
    • Internal Medicine Department, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
    • Braz J Infect Dis. 2021 Jan 1; 25 (1): 101541.

    AbstractOrganizing pneumonia emerges as a late phase complication of COVID-19. Corticosteroids are standard therapy for organizing pneumonia, but the question of whether an approach with high dose corticosteroids would be beneficial for patients with organizing pneumonia secondary to COVID-19 remains to be answered. Herein we report a series of three patients, one male and two females, mean age 58.3 years old, admitted for COVID-19 with severe pulmonary disease requiring ventilatory support. The patients underwent chest computed tomography scans due to maintained hypoxemia, which showed a pattern compatible with organizing pneumonia. The patients were treated with a high dose of corticosteroids (prednisone 1 mg/kg PO), showing marked clinical improvement, and decreasing oxygen flow ratio demand. They were discharged after a mean period of 6.3 days of hospitalization. Our report suggests that patients with COVID-19 with organizing pneumonia might benefit from high dose corticosteroids as an adjuvant therapy.Copyright © 2021 Brazilian Society of Infectious Diseases. Published by Elsevier España, S.L.U. All rights reserved.

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