• Am. J. Trop. Med. Hyg. · May 1999

    Case Reports

    Short report: Diagnosis of tick-borne relapsing fever by the quantitative buffy coat fluorescence method.

    • G Chatel, M Gulletta, A Matteelli, A Marangoni, L Signorini, O Oladeji, and S Caligaris.
    • Clinic of Infectious and Tropical Diseases, University of Brescia, Italy.
    • Am. J. Trop. Med. Hyg. 1999 May 1; 60 (5): 738-9.

    AbstractThe quantitative buffy coat (QBC) parasite detection method is a sensitive and specific tool for the diagnosis of malaria parasites. It is also useful for the diagnoses of other hemoparasites, including Trypanosoma, Babesia, and Leptospira. We report a case of relapsing fever diagnosed by this technique in a short-term traveler from Senegal. The diagnosis was confirmed by the standard Giemsa hemoscopy and by the identification of significant titers of antibodies to Borrelia spp. of tick-borne relapsing fevers by specific immunofluorescence and Western blot tests. The QBC technique seems to be useful in the diagnosis of tick-borne relapsing fever in blood samples and should be included in the management of fever in the traveler returning from tropical regions.

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