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- Day-Yu Chao, Kuang-Fu Cheng, Ying-Hen Hsieh, Tsai-Chung Li, Trong-Neng Wu, Chiu-Ying Chen, Chen-An Tsai, Jin-Hwa Chen, Hsien-Tsai Chiu, Jang-Jih Lu, Mei-Chi Su, Yu-Hsin Liao, and CIDER.
- Graduate Institute of Microbiology and Public Health, College of Veterinary Medicine, National Chung-Hsing University, Taichung 401, Taiwan. dychao@nchu.edu.tw
- Vaccine. 2011 Jan 17; 29 (4): 617-23.
AbstractThe serological response of the current 2009 H1N1 pandemic influenza monovalent vaccine in children exhibiting high baseline seropositive rate was evaluated though a community-based household study. Seroprotection rate of >90% and seroconversion rate of >50% were observed in children one month after receiving the pandemic vaccine. Among children with low baseline antibody titer, a significant lower seroconversion rate (55%) was observed in children who received seasonal trivalent inactivated vaccine (TIV) prior to pandemic vaccine, when compared with those receiving the pandemic vaccine only (86%). Persistence of antibody against the pandemic influenza virus was observed 6 months after vaccination in >80% of children presenting seroprotective antibody levels.Copyright © 2010 Elsevier Ltd. All rights reserved.
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