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- Daniel L Neuman and Andrea L Chadwick.
- From the Department of Anesthesiology, University of Kansas Medical Center, Kansas City, Kansas.
- A A Pract. 2021 May 17; 15 (5): e01475e01475.
AbstractBurning mouth syndrome is a chronic pain condition characterized by a burning sensation of the oropharynx. The pathophysiology of burning mouth syndrome includes peripheral and central sensitization. Treatment is generally aimed at symptom reduction. We describe a woman in her seventh decade with burning mouth syndrome that had been refractory to treatment for nearly a decade. Low-dose naltrexone has been reported to provide analgesia in central sensitization states and was successful in reducing pain severity in our patient. We conclude that low-dose naltrexone may be a therapeutic option for patients with burning mouth syndrome who are refractory to conventional therapies.Copyright © 2021 International Anesthesia Research Society.
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