• Elena Bardellini, Francesca Amadori, Federica Veneri, Giulio Conti, Alberto Paderno, and Alessandra Majorana.
• Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, School of Paediatric Dentistry- Dental Clinic, University of Brescia, ASST-Spedali Civili of Brescia, 25133, Brescia, Italy. elena.bardellini@unibs.it.
• Ir J Med Sci. 2022 Apr 1; 191 (2): 801-805.

AimThe aim of this study was to investigate the therapies administered to Italian adolescents with primary herpetic gingivostomatitis (PHGS) METHODS: The medical records of 74 adolescents with PHSG were reviewed. The following data were recorded: age, gender, day of onset, type of treatment, lesions' severity, pain scoring, eating, and drinking ability. The oral examination was performed at the first evaluation (T0) and after one week (T1).ResultsAll patients showed up at the first visit at least 48 h after the onset of symptoms. No patient was prescribed an antiviral therapy. An antibiotic therapy was prescribed in order to prevent secondary bacterial infections. Fifteen patients had been treated with non alcoholic chlorhexidine rinses (group A), 29 patients with non alcoholic chlorhexidine rinses plus hyaluronic acid gel (group B); 30 patients with non alcoholic chlorhexidine rinses plus Mucosyte® (group C). A significant improvement of the pain scoring and lesions' severity was noted in group C.ConclusionIn Italian adolescents, PHGS is diagnosed at least 48 h after onset and the antibiotic therapy is widely prescribed in order to prevent overinfections. Among topical therapies, an association of verbascoside and sodium hyaluronhate seems to favour a faster healing.© 2021. The Author(s).

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