• J Fam Pract · Mar 2018

    HelpDesk: How accurate are point-of-care urine drug screens in patients taking chronic opioid therapy?

    • Brooke Hall and Sarah Daly.
    • Utah Valley Family Medicine Residency, Provo, UT, USA.
    • J Fam Pract. 2018 Mar 1; 67 (3): 177.

    AbstractIn adults treated with opioids for chronic pain, point-of-care urine drug screens (immunoassays) for detecting opioids show a false-negative rate of 1.9%, a sensitivity of 92%, and a specificity of 93% compared with the gold-standard liquid chromatography tandem mass spectrometry. Oxycodone has the highest rate of false-negative results at 25%; methadone has the lowest rate at 4% to 6% (strength of recommendation: A, 2 blinded diagnostic accuracy studies with similar results).

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