• Support Care Cancer · Nov 2021

    Clinical assessment of chemotherapy-induced peripheral neuropathy: a discrete choice experiment of patient preferences.

    • Alice Yu, Deborah Street, Rosalie Viney, Stephen Goodall, Alison Pearce, Philip Haywood, Marion Haas, Eva Battaglini, David Goldstein, Hannah Timmins, and Susanna B Park.
    • University of Technology Sydney (CHERE), Sydney, NSW, Australia. alice.yu@chere.uts.edu.au.
    • Support Care Cancer. 2021 Nov 1; 29 (11): 6379-6387.

    PurposeUp to 40% of cancer patients treated with neurotoxic chemotherapies experience chemotherapy-induced peripheral neuropathy (CIPN). Currently, there is no gold standard assessment tool for CIPN and there is little information in the literature on patient preferences for such assessments. This study aims to address this gap by identifying the features of a CIPN assessment tool that cancer patients value.MethodsAn online discrete choice experiment (DCE) survey of neurotoxic chemotherapy-treated patients was implemented. Respondents completed 8 choice questions each. In each choice question, they chose between two hypothetical CIPN assessment tools, each described by six attributes: impact on quality of life; level of nerve damage detected; questionnaire length; physical tests involved; impact on clinic time; impact on care.ResultsThe survey was completed by 117 respondents who had a range of cancers of which breast cancer was the most common. Respondents favoured an assessment tool that includes a physical test and that asks about impact on quality of life. Respondents were strongly opposed to clinicians, alone, deciding how the results of a CIPN assessment might influence their care especially their chemotherapy treatment. They were concerned about small changes in their CIPN, independent of clinical relevance. Respondents were willing to add half an hour to the usual clinic time to accommodate the CIPN assessment.ConclusionThe findings of this DCE will assist clinicians in choosing an assessment tool for CIPN that is satisfactory to both clinician and patient.© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

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