• Hi-Jae Heiroth, Markus J Riemenschneider, Hans-Jakob Steiger, and Daniel Hänggi.
• Department of Neurosurgery, Heinrich-Heine University, Düsseldorf, Germany. Hi-Jae.Heiroth@uniduesseldorf.de
• Neurosurgery. 2009 Jul 1; 65 (1): E212-3; discussion E213.

ObjectiveNeurinomas of the hypoglossal nerve are very rare. They are mostly located intracranially or combined intra- and extracranially, resulting in the so-called dumbbell shape. The isolated extracranial localization of the neurinoma of the hypoglossal nerve adjacent to the cranial base as described in this case report is extremely rare.Clinical PresentationThe 23-year-old patient presented with recurring headaches. She had right-sided hypoglossal nerve palsy for approximately 5 to 6 years. Magnetic resonance imaging revealed an extracranial tumor with contact to the cranial base originating from the hypoglossal nerve.InterventionThe tumor was extirpated surgically and verified histologically as a schwannoma of the hypoglossal nerve.ConclusionPathologies of the hypoglossal nerve as such are very rare within the clinical landscape. When a tumor occurs, its shape and location must be analyzed to establish whether, or by which approach, surgical removal is feasible. Although very unusual, the mere extracranial occurrence of a hypoglossal neurinoma at the cranial base should be considered a differential diagnosis.

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