• Nihon Geka Gakkai zasshi · May 2004

    [Evidence-based surgical therapy: the significance of randomized controlled trials].

    • Hiroyuki Katoh.
    • Department of Surgery Oncology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
    • Nihon Geka Gakkai Zasshi. 2004 May 1; 105 (5): 329-33.

    AbstractEvidence-based medicine supplies the information to solve clinical questions but there are specific problems of randomized controlled trials in surgery. First, placebo-controlled trials are need to determine the placebo effects, but patients sometimes refuse the placebo surgery. Furthermore, it remains difficult to decide on standard surgical procedures because the participating surgeons vary in skill and experience. However, randomized controlled trials are essential for the further development of a high-quality surgical standard.

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