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Diagn. Microbiol. Infect. Dis. · Sep 2020
COVID-19: Understanding the science of antibody testing and lessons from the HIV epidemic.
- Stanley H Weiss and Gary P Wormser.
- Department of Medicine, Rutgers New Jersey Medical School, Newark, NJ, U.S.A.; Department of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, NJ, U.S.A.. Electronic address: weiss@rutgers.edu.
- Diagn. Microbiol. Infect. Dis. 2020 Sep 1; 98 (1): 115078.
AbstractPotential pitfalls in the development, deployment and interpretation of antibody tests for COVID-19 are discussed. Lessons learned from the experience with the introduction of antibody tests for HIV are highlighted.Each test will need to be separately vetted for performance and clinical implementation based upon rigorous clinical trial data. The issues we highlight will also be similarly important for vaccine and therapeutic drug efficacy trials.Copyright © 2020 Elsevier Inc. All rights reserved.
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