• Clinical pediatrics · Apr 2009

    Review Case Reports

    Acute hemorrhagic edema of infancy: report of 4 cases and review of the current literature.

    • Michael Karremann, Alexander J Jordan, Nellie Bell, Michael Witsch, and Matthias Dürken.
    • Department of Pediatrics, University Hospital Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. michael.karremann@kikli.ma.uni-heidelberg.de
    • Clin Pediatr (Phila). 2009 Apr 1; 48 (3): 323-6.

    AbstractAcute hemorrhagic edema of infancy (AHEI) is a cutaneous leukocytoclastic vasculitis that usually occurs in children younger than 2 years of age. It is a rare disease characterized by mild fever, a violent onset of hemorrhagic skin lesions, and edema usually followed by a spontaneous and complete recovery. Although the etiology is unknown, AHEI often follows infections, drug treatment, or vaccination. In the present report, the authors describe 4 cases of AHEI and review the relevant literature.

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